#1-Blog – Looking for new ANTI-COVID drugs?
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We hereby present the first blog of World of Pharmacy. Enjoy reading!
The globe has crossed more than a year struggling with this COVID-19 pandemic. Each one has faced a different hit by this lockdown. Today, we will be talking from the researchers’ perspective and understand their soulful efforts to end this pandemic. Their months of hard work in the labs have now fruited into increased hopes for treatment of this infection. Studies showed that the virus enters the cells using our body’s enzyme and not it’s own. So, didn’t this decrease the hopes to get a virus-specific drug?
Moving on to the main part of this blog, currently, we have a variety of drugs for treating various disease conditions. Scientists found that these drugs also have many other effects. Amazingly, some of them were also active against “SARS CoV-2”. This is called drug repurposing. Drugs like Remdesivir, Lapatinib, Trametinib, Chloroquine, Hydroxychloroquine, Lopinavir, Ritonavir, and Ivermectin have shown promising results.
Well, did you ever wonder how COVID-19 infection becomes fatal? The answer is cytokines, which are proteins released by the immune system. When this infection increases beyond a limit, a ‘cytokine storm’ occurs wherein the immune system releases a different set of cytokines that increase inflammation. This not only harms healthy cells along with the virus but also worsens the patient’s condition. Hence, immunomodulators like Dexamethasone, Hydrocortisone, Budesonide, Azithromycin, Doxycycline, Tocilizumab, etc, are used.
Advancement in the medical field now allows treatment with antibody-rich plasma from people recovered from COVID-19 to treat severe cases. Combinations of all these drugs are under clinical trials & let us hope that the outcome of these trials will give doctors new ways to combat COVID 19 infection.
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